SCHEMBL15744530

SCHEMBL15744530

CCCc1ccc(CCc2cc(F)c(C(F)(F)OC(F)(F)F)c(F)c2)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.35
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
PDK2 Q15119 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
THRB P10828 1/20 0.31
NR3C2 P08235 1/20 0.30
DAO P14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15744450 0.93 S1PR1 (0.32) S1PR1
SCHEMBL15745162 0.91 RARB (0.36) S1PR1HTR2AHTR2CCNR1THRB
SCHEMBL15744408 0.90 THRB (0.34) S1PR1PDK2CNR1CNR2THRB
SCHEMBL15744843 0.87 RARB (0.33) S1PR1CNR1
SCHEMBL15745179 0.86 MCL1 (0.35) THRBDAO
SCHEMBL13002672 0.85 DAO (0.41) S1PR1HTR2AHTR2CPDK2CNR1
SCHEMBL15744985 0.84 MAOB (0.34) S1PR1
SCHEMBL15744304 0.81 PDK2 (0.37) S1PR1PDK2CNR1CNR2
SCHEMBL15744334 0.80 RARB (0.38) S1PR1THRB
SCHEMBL15744557 0.80 RARB (0.38) S1PR1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
EP-2735599-A1 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC Corporation (JP) 2014-05-28 EP disclosed