Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725208 | 0.96 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10TSHRCHRM2 | |
| SCHEMBL6906507 | 0.96 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10TSHRCHRM2 | |
| SCHEMBL20511559 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL22486534 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRCHRM1 | |
| SCHEMBL30104599 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL30104659 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL30104680 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL22486478 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRCHRM1 | |
| SCHEMBL13235972 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRCHRM1 | |
| SCHEMBL6900291 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9517292-B2 | Polymer for creating hemocompatible surface | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2016-12-13 | — | — | US | disclosed |
| US-20140147485-A1 | POLYMER FOR CREATING HEMOCOMPATIBLE SURFACE | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140147485-A1 | POLYMER FOR CREATING HEMOCOMPATIBLE SURFACE | PHOSPHO1, SGMS1, CHKB | ALDH1A1 4070/4885LMNA 1360/4885HSD17B10 1781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.