SCHEMBL15744984

SCHEMBL15744984

CCCCc1ccc2cc(-c3ccc(C(F)(F)Oc4cc(F)c(-c5cc(F)c(C(F)(F)OC(F)(F)F)c(F)c5)c(F)c4)cc3)ccc2c1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RARB P10826 2/20 0.33
RARA P10276 1/20 0.33
RARG P13631 1/20 0.33
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745164 0.90 HRH3 (0.34) HRH3
SCHEMBL15744836 0.89 HRH3 (0.33) HRH3
SCHEMBL15744952 0.88 SERPINE1 (0.33) HRH3
SCHEMBL15745194 0.88 MAOB (0.32) RARBRARARARG
SCHEMBL15744926 0.87 RARB (0.41) RARBRARARARGHRH3
SCHEMBL15745081 0.87 RARB (0.37) RARBRARARARG
SCHEMBL15744588 0.86 HRH3 (0.35) RARBRARARARGHRH3
SCHEMBL15744364 0.86
SCHEMBL15745054 0.85 KIF11 (0.32)
SCHEMBL15744503 0.85 ESR1 (0.34) RARBRARARARGHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed