Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.37 |
| ▸ | CTSK | P43235 | 4/20 | 0.37 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | BHMT | Q93088 | 4/20 | 0.35 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335295 | 0.89 | MEN1 (0.43) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL15745438 | 0.86 | MEN1 (0.48) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL994583 | 0.83 | MEN1 (0.53) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL997508 | 0.83 | MEN1 (0.53) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL994584 | 0.83 | MEN1 (0.53) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL12582748 | 0.82 | MEN1 (0.50) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL15739037 | 0.82 | MEN1 (0.50) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL12463713 | 0.82 | MEN1 (0.50) | MEN1GAAKMT2ACTSSCTSK | |
| Chloromethane SCHEMBL17911911 | 0.82 | MEN1 (0.51) | MEN1GAAKMT2ACTSSCTSK | |
| Hydrochloric Acid SCHEMBL668972 | 0.82 | MEN1 (0.51) | MEN1GAAKMT2ACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140148576-A1 | Traceless Ubiquitination | MEDICAL RESEARCH COUNCIL (GB) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148576-A1 | Traceless Ubiquitination | KARS1, GARS1, QARS1 | MEN1 3625/4885GAA 2363/4885KMT2A 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.