Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16421936 | 1.00 | SIGMAR1 (0.53) | SIGMAR1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL7768067 | 0.94 | SIGMAR1 (0.58) | SIGMAR1MEN1KMT2AKDM4EMAOB | |
| SCHEMBL8720913 | 0.94 | SIGMAR1 (0.58) | SIGMAR1MEN1KMT2AKDM4EMAOB | |
| SCHEMBL7764937 | 0.94 | SIGMAR1 (0.58) | SIGMAR1MEN1KMT2AKDM4EMAOB | |
| SCHEMBL7764359 | 0.94 | SIGMAR1 (0.58) | SIGMAR1MEN1KMT2AKDM4EMAOB | |
| SCHEMBL8722902 | 0.94 | SIGMAR1 (0.58) | SIGMAR1MEN1KMT2AKDM4EMAOB | |
| SCHEMBL8724611 | 0.94 | SIGMAR1 (0.58) | SIGMAR1MEN1KMT2AKDM4EMAOB | |
| SCHEMBL8720392 | 0.94 | SIGMAR1 (0.58) | SIGMAR1MEN1KMT2AKDM4EMAOB | |
| SCHEMBL8254170 | 0.92 | KDM4E (0.50) | SIGMAR1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL7128368 | 0.92 | SIGMAR1 (0.55) | SIGMAR1MEN1KMT2AKDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980925-B2 | Antimicrobial amphiphiles and methods for their use | JAMES MADISON INNOVATIONS, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140148487-A1 | ANTIMICROBIAL AMPHIPHILES AND METHODS FOR THEIR USE | James Madison Innovations, Inc, (US) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148487-A1 | ANTIMICROBIAL AMPHIPHILES AND METHODS FOR THEIR USE | ANXA5, ANXA4, ANXA6 | SIGMAR1 1289/4885MEN1 3309/4885KMT2A 4573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.