SCHEMBL15745663

SCHEMBL15745663

CCCc1cc(N)c(C(C)(O)C(F)(F)F)cc1Cc1cc(C(C)(O)C(F)(F)F)c(N)cc1CCC

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745675 0.91 TYR (0.34)
SCHEMBL15745667 0.88 AR (0.35) ARSMN1; SMN2
SCHEMBL15764636 0.86 SMN1; SMN2 (0.45) ARSMN1; SMN2
SCHEMBL15745674 0.80 ALDH1A1 (0.48) ARSMN1; SMN2
SCHEMBL15745670 0.80 CFTR (0.35) ARSMN1; SMN2
SCHEMBL19465257 0.79 SMN1; SMN2 (0.39) ARSMN1; SMN2
SCHEMBL15745672 0.78 CFTR (0.33) ARSMN1; SMN2
SCHEMBL15745678 0.78 AR (0.36) ARSMN1; SMN2
SCHEMBL15745676 0.78 SMN1; SMN2 (0.33) ARSMN1; SMN2
SCHEMBL15764646 0.78 SMN1; SMN2 (0.43) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9793483-B2 Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-10-17 US disclosed
US-20140148571-A1 Hexafluoroisopropanol Group-Containing Diamine, Polyimide And Polyamide Using Same, Cyclized Product Thereof, And Method For Producing Same CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-29 US disclosed