Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 14/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 2/20 | 0.35 |
| ▸ | GCKR | Q14397 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15746923 | 0.87 | SMN1; SMN2 (0.50) | HSD11B1SMN1; SMN2GCKGCKRCA12 | |
| SCHEMBL15957675 | 0.83 | SMN1; SMN2 (0.42) | HSD11B1SMN1; SMN2AR | |
| SCHEMBL15745673 | 0.80 | SMN1; SMN2 (0.40) | HSD11B1SMN1; SMN2AR | |
| SCHEMBL10002089 | 0.78 | SMN1; SMN2 (0.42) | HSD11B1SMN1; SMN2ARCA12CA1 | |
| SCHEMBL15745669 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2AR | |
| SCHEMBL15745664 | 0.77 | SMN1; SMN2 (0.36) | HSD11B1SMN1; SMN2ARCA2ABCC9 | |
| SCHEMBL15745677 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2AR | |
| SCHEMBL15831665 | 0.77 | SMN1; SMN2 (0.41) | HSD11B1SMN1; SMN2ARCA12CA1 | |
| SCHEMBL15745668 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2AR | |
| SCHEMBL19461412 | 0.75 | SMN1; SMN2 (0.37) | SMN1; SMN2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9793483-B2 | Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20140148571-A1 | Hexafluoroisopropanol Group-Containing Diamine, Polyimide And Polyamide Using Same, Cyclized Product Thereof, And Method For Producing Same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-05-29 | — | — | US | disclosed |