Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 3/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15745673 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2MAPK1CYP3A4TSHRAR | |
| SCHEMBL10002089 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPK1ARALDH1A1CFTR | |
| SCHEMBL15745669 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPK1CYP3A4TSHRAR | |
| SCHEMBL15745677 | 0.85 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPK1CYP3A4TSHRAR | |
| SCHEMBL15831665 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPK1ARALDH1A1CFTR | |
| SCHEMBL15957658 | 0.85 | AR (0.44) | SMN1; SMN2ARALDH1A1HSD11B1POLB | |
| SCHEMBL19461412 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2ARALDH1A1 | |
| SCHEMBL15745668 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPK1CYP3A4TSHRAR | |
| SCHEMBL15745674 | 0.84 | ALDH1A1 (0.48) | SMN1; SMN2ARALDH1A1CFTR | |
| SCHEMBL15745671 | 0.83 | HSD11B1 (0.39) | SMN1; SMN2ARHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809451-B2 | Fluorinated dicarboxylic acid derivative and polymer obtained therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20110301305-A1 | Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2011-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301305-A1 | Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom | MCCC2, AFF2, F13A1 | SMN1; SMN2 3546/4885MAPK1 1655/4885CYP3A4 2766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.