SCHEMBL15745692

SCHEMBL15745692

Cc1ccc(Cc2ccc(-n3c(=O)c4cc5c(=O)n(C)c(=O)c5cc4c3=O)c(C(C)(O)C(F)(F)F)c2)cc1C(C)(O)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 6/20 0.37
PGR P06401 6/20 0.34
AR P10275 1/20 0.34
NR3C2 P08235 3/20 0.33
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15831657 0.78 ESR2 (0.41) NR3C1PGRARNR3C2POLB
SCHEMBL15745689 0.77 PGR (0.34) PGRARKDM4EPOLBGAA
SCHEMBL15745684 0.76 PGR (0.32) PGRAR
SCHEMBL15745691 0.75 NQO1 (0.39) KDM4EPOLBGAA
SCHEMBL15745820 0.74 ESR1 (0.37) NR3C1PGRARNR1H3
SCHEMBL16838065 0.74 ESR2 (0.38) NR3C1PGRARNR3C2POLB
SCHEMBL13294599 0.72 PGR (0.39) NR3C1PGRARNR3C2KDM4E
SCHEMBL12724507 0.72 SMN1; SMN2 (0.46) NR3C1PGRARNR3C2KDM4E
SCHEMBL15831667 0.70 NR1H3 (0.36) NR3C1NR1H3
SCHEMBL19465279 0.68 PGR (0.30) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9793483-B2 Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-10-17 US disclosed
US-20140148571-A1 Hexafluoroisopropanol Group-Containing Diamine, Polyimide And Polyamide Using Same, Cyclized Product Thereof, And Method For Producing Same CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-29 US disclosed