SCHEMBL15746148

SCHEMBL15746148

Nc1cc(Oc2ccc(N)c(C(O)(C(F)(F)F)C(F)(F)F)c2)ccc1C(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.54
NR4A1 P22736 1/20 0.46
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
MAPT P10636 3/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPK1 P28482 2/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HSD17B10 Q99714 2/20 0.37
ALDH1A1 P00352 2/20 0.37
GAA P10253 2/20 0.37
GLA P06280 1/20 0.37
POLB P06746 1/20 0.37
HPGD P15428 1/20 0.37
ATM Q13315 1/20 0.37
FFAR4 Q5NUL3 2/20 0.32
AR P10275 3/20 0.32
SCN9A Q15858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10036669 0.93 SMN1; SMN2 (0.61) SMN1; SMN2NR4A1MEN1KMT2AMAPT
SCHEMBL26327982 0.90 SMN1; SMN2 (0.51) SMN1; SMN2NR4A1MEN1KMT2AMAPT
SCHEMBL13294535 0.89 SMN1; SMN2 (0.56) SMN1; SMN2NR4A1MEN1KMT2AMAPT
SCHEMBL10036539 0.87 SMN1; SMN2 (0.54) SMN1; SMN2NR4A1MEN1KMT2AMAPT
SCHEMBL13588163 0.84 SMN1; SMN2 (0.69) SMN1; SMN2NR4A1MEN1KMT2AMAPT
SCHEMBL13588164 0.84 SMN1; SMN2 (0.59) SMN1; SMN2NR4A1MEN1KMT2AMAPT
SCHEMBL15745076 0.80 NR4A1 (0.42) SMN1; SMN2NR4A1MAPTMAPK1ALDH1A1
SCHEMBL13294541 0.80 SMN1; SMN2 (0.47) SMN1; SMN2NR4A1MEN1KMT2AMAPT
SCHEMBL13294543 0.79 SMN1; SMN2 (0.46) SMN1; SMN2NR4A1MEN1KMT2AMAPT
SCHEMBL15746149 0.78 SMN1; SMN2 (0.48) SMN1; SMN2NR4A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287178-A1 Fluorinated Diamine or Salt Thereof, Method for Producing Fluorinated Diamine or Salt Thereof, Polyamide, Method for Producing Polyamide, Polyamide Solution, Cyclized Polyamide, Method for Producing Cyclized Polyamide, Insulation for High-Frequency Electronic Component, Method for Producing Insulation for High-Frequency Electronic Component, High-Frequency Electronic Component, High-Frequency Appliance, and Insulating Material for Producing High-Frequency Electronic Component CENTRAL GLASS COMPANY, LIMITED (JP) 2023-09-14 US disclosed
EP-4190768-A1 FLUORINATED DIAMINE OR SALT THEREOF, METHOD FOR PRODUCING FLUORINATED DIAMINE OR SALT THEREOF, POLYAMIDE, METHOD FOR PRODUCING POLYAMIDE, POLYAMIDE SOLUTION, CYCLIZED POLYAMIDE, METHOD FOR PRODUCING CYCLIZED POLYAMIDE, INSULATING MATERIAL FOR HIGH-FREQUENCY ELECTRONIC COMPONENT, METHOD FOR PRODUCING INSULATING MATERIAL FOR HIGH-FREQUENCY ELECTRONIC COMPONENT, HIGH-FREQUENCY ELECTRONIC COMPONENT, HIGH-FREQUENCY APPLIANCE, AND INSULATING MATERIAL FOR PRODUCING HIGH-FREQUENCY ELECTRONIC COMPONENT Central Glass Company, Limited (JP) 2023-06-07 EP disclosed
US-9056285-B2 Gas separation membrane CENTRAL GLASS COMPANY, LIMITED (JP) 2015-06-16 US disclosed
US-20140144325-A1 Gas Separation Membrane CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-29 US disclosed