SCHEMBL103529

SCHEMBL103529

O=C(Cl)c1cc2ccccc2s1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.69
HDAC1 Q13547 2/20 0.65
HDAC3 O15379 1/20 0.65
HDAC4 P56524 1/20 0.65
HDAC7 Q8WUI4 1/20 0.65
HDAC2 Q92769 1/20 0.65
HDAC10 Q969S8 1/20 0.65
HDAC11 Q96DB2 1/20 0.65
HDAC8 Q9BY41 1/20 0.65
HDAC6 Q9UBN7 1/20 0.65
HDAC9 Q9UKV0 1/20 0.65
HDAC5 Q9UQL6 1/20 0.65
SLC9A1 P19634 2/20 0.57
CNR1 P21554 1/20 0.56
CNR2 P34972 1/20 0.56
DYRK1A Q13627 1/20 0.56
HRH4 Q9H3N8 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
TMIGD3 P0DMS9 1/20 0.50
ADORA1 P30542 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6321234 0.83 BCL2L1 (0.74) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL31356465 0.83 BCL2L1 (0.74) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL7209477 0.83 BCL2L1 (0.74) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL93858 0.82 BCL2L1 (1.00) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL5355955 0.82 BCL2L1 (0.71) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL29438783 0.82 BCL2L1 (1.00) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL11269271 0.80 BCL2L1 (0.64) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL16599119 0.80 BCL2L1 (0.69) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL826496 0.80 BCL2L1 (0.69) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL19880937 0.80 BCL2L1 (0.69) BCL2L1HDAC1HDAC3HDAC4HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 621 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017060287-A1 PROCESS FOR THE PREPARATION OF ENCENICLINE FROM 7-CHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID CHLORIDE AND (R)-QUINUCLIDIN-3-AMINE IN THE PRESENCE OF IMIDAZOLE SANDOZ AG (CH) 2017-04-13 WO claimed
CN-121130933-A Preparation method and application of lignin-derived carbon-modified carbon nitride catalyst 福建农林大学 2025-12-16 CN disclosed
US-20250248990-A1 QUINOLINES THAT MODULATE SERCA AND THEIR USE FOR TREATING DISEASE NEURODON CORPORATION 2025-08-07 US disclosed
CN-113631536-B Fluorene derivative and use thereof 日产化学株式会社 2025-06-10 CN disclosed
CN-119409634-A HSA fluorescent probe and synthesis and application thereof 河北大学 2025-02-11 CN disclosed
CN-119241520-A Oxime ester photoinitiator and photopolymerization composition 武汉尚赛光电科技有限公司 2025-01-03 CN disclosed
US-12144806-B2 Quinolines that modulate SERCA and their use for treating disease NEURODON CORPORATION (US) 2024-11-19 US disclosed
CN-118715206-A Novel HDAC inhibitors and therapeutic uses thereof 探戈医药股份有限公司 2024-09-27 CN disclosed
US-20240277694-A1 QUINOLINES THAT MODULATE SERCA AND THEIR USE FOR TREATING DISEASE NEURODON CORPORATION 2024-08-22 US disclosed
CN-116253676-B Amide compound, polymer film containing amide compound, and preparation method and application of polymer film 中国科学院理化技术研究所 2024-07-12 CN disclosed
US-5089489-A Enzyme inhibitors FARMITALIA CARLO ERBA S.R.L. (IT) 1992-02-18 US disclosed
EP-0243173-B1 NEW DIPHOSPHONIC ACID COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-06-26 EP disclosed
US-4963536-A INHIBIT BONE RESORPTION FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-10-16 US disclosed
US-4954493-A ENZYME INHIBITORS FARMITALIA CARLO ERBA S.R.L. (IT) 1990-09-04 US disclosed
EP-0187487-B1 BENZOTHIOPHENES AND BENZOFURANS HAVING ANTIALLERGIC ACTIVITY WARNER-LAMBERT COMPANY (US) 1990-08-29 EP disclosed
US-4857513-A Diphosphonic acid compounds, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISIWA PHARMACEUTICAL CO., LTD. (JP) 1989-08-15 US disclosed
EP-0243173-A2 New diphosphonic acid compounds, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-10-28 EP disclosed
US-4703053-A Benzothiophenes and benzofurans and antiallergic use thereof WARNER-LAMBERT COMPANY (US) 1987-10-27 US disclosed
EP-0187487-A1 Benzothiophenes and benzofurans having antiallergic activity WARNER-LAMBERT COMPANY (US) 1986-07-16 EP disclosed
US-4514399-A N-N'substituted polymethylene diamines ADIR (FR) 1985-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12144806-B2 Quinolines that modulate SERCA and their use for treating disease ATP2A1, ATP2A3, ATP2A2 BCL2L1 1435/4885HDAC1 2929/4885HDAC3 3144/4885
US-20250248990-A1 QUINOLINES THAT MODULATE SERCA AND THEIR USE FOR TREATING DISEASE ATP2A1, ATP2A3, ATP2A2 BCL2L1 1435/4885HDAC1 2929/4885HDAC3 3144/4885
US-20240277694-A1 QUINOLINES THAT MODULATE SERCA AND THEIR USE FOR TREATING DISEASE ATP2A1, ATP2A3, ATP2A2 BCL2L1 1435/4885HDAC1 2929/4885HDAC3 3144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.