Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16512646 | 0.85 | XPO1 (0.43) | XPO1PTPN1 | |
| SCHEMBL15746163 | 0.85 | XPO1 (0.43) | XPO1PTPN1 | |
| SCHEMBL11427232 | 0.77 | — | — | |
| SCHEMBL15746169 | 0.76 | PTPN1 (0.36) | XPO1PTPN1HTT | |
| SCHEMBL11988739 | 0.76 | PTPN1 (0.40) | XPO1PTPN1KDM4ELMNAMAPT | |
| SCHEMBL512370 | 0.76 | XPO1 (0.39) | XPO1PTPN1HTT | |
| SCHEMBL30590682 | 0.76 | PTPN1 (0.40) | XPO1PTPN1KDM4ELMNAMAPT | |
| SCHEMBL4917217 | 0.73 | PTPN1 (0.40) | XPO1PTPN1KDM4ELMNAMAPT | |
| SCHEMBL5307393 | 0.73 | PTPN1 (0.40) | XPO1PTPN1KDM4ELMNAMAPT | |
| SCHEMBL4926758 | 0.73 | PTPN1 (0.40) | XPO1PTPN1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073884-B2 | Anti-inflammatory and quorum sensing inhibition compounds and methods of making and using them | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-07-07 | — | — | US | disclosed |
| US-20140147481-A1 | ANTI-INFLAMMATORY AND QUORUM SENSING INHIBITION COMPOUNDS AND METHODS OF MAKING AND USING THEM | UNIVERSITY OF RHODE ISLAND RESEARCH FOUNDATION (US) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140147481-A1 | ANTI-INFLAMMATORY AND QUORUM SENSING INHIBITION COMPOUNDS AND METHODS OF MAKING AND USING THEM | CGAS, CD47, LGALS1 | XPO1 2997/4885PTPN1 1613/4885KDM4E 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.