Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | CDH1 | P12830 | 1/20 | 0.54 |
| ▸ | APC | P25054 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967657 | 1.00 | TDP1 (0.54) | TDP1CDH1APCCTNNB1TCF7L2 | |
| Hydrochloric Acid SCHEMBL11208994 | 0.98 | TDP1 (0.53) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL11144403 | 0.93 | TDP1 (0.54) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL29967465 | 0.93 | TDP1 (0.54) | TDP1CDH1APCCTNNB1TCF7L2 | |
| Hydrochloric Acid SCHEMBL10584298 | 0.92 | TDP1 (0.53) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL5007899 | 0.86 | ALDH1A1 (0.46) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL25527753 | 0.85 | ALDH1A1 (0.49) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL15060475 | 0.81 | GSK3B (0.46) | CDH1APCCTNNB1TCF7L2RAB9A | |
| SCHEMBL21818455 | 0.81 | HTT (0.52) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL11088871 | 0.81 | ALDH1A1 (0.62) | TDP1CDH1APCCTNNB1TCF7L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3614141-B1 | STABLE URINE INDICATOR WITH LONG-TERM DETECTION AND METHOD FOR ITS PREPARATION | AXAGARIUS GMBH & CO KG (DE) | 2022-10-05 | — | — | EP | claimed |
| US-20200064317-A1 | Stable Urine Indicator with Long-Term Detection | AXAGARIUS GMBH & CO. KG (DE) | 2020-02-27 | — | — | US | claimed |
| US-20200064317-A1 | Stable Urine Indicator with Long-Term Detection | AXAGARIUS GMBH & CO. KG (DE) | 2020-02-27 | — | — | US | disclosed |
| EP-1751149-B1 | BICYCLIC-SUBSTITUTED AMINES HAVING CYCLIC-SUBSTITUTED MONOCYCLIC SUBSTITUENTS | ABBOTT LAB (US) | 2012-06-06 | — | — | EP | disclosed |
| EP-1751149-B1 | BICYCLIC-SUBSTITUTED AMINES HAVING CYCLIC-SUBSTITUTED MONOCYCLIC SUBSTITUENTS | ABBOTT LAB (US) | 2012-06-06 | — | — | EP | disclosed |
| EP-2308873-A1 | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents | Abbott Laboratories (US) | 2011-04-13 | — | — | EP | disclosed |
| EP-2308873-A1 | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents | Abbott Laboratories (US) | 2011-04-13 | — | — | EP | disclosed |
| EP-2258703-A1 | Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands | Abbott Laboratories (US) | 2010-12-08 | — | — | EP | disclosed |
| US-7205316-B2 | Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands | ABBOTT LABORATORIES (US) | 2007-04-17 | — | — | US | disclosed |
| US-7205316-B2 | Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands | ABBOTT LABORATORIES (US) | 2007-04-17 | — | — | US | disclosed |
| EP-1751130-A2 | TRI- AND BI-CYCLIC HETEROARYL HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2007-02-14 | — | — | EP | disclosed |
| EP-1751149-A1 | BICYCLIC-SUBSTITUTED AMINES HAVING CYCLIC-SUBSTITUTED MONOCYCLIC SUBSTITUENTS | ABBOTT LABORATORIES (US) | 2007-02-14 | — | — | EP | disclosed |
| US-7098222-B2 | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents | ABBOTT LABORATORIES (US) | 2006-08-29 | — | — | US | disclosed |
| US-20050272736-A1 | Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands | ABBVIE INC. | 2005-12-08 | — | — | US | disclosed |
| US-20050272728-A1 | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents | ABBVIE INC. | 2005-12-08 | — | — | US | disclosed |
| WO-2005113536-A2 | TRI- AND BI-CYCLIC HETEROARYL HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2005-12-01 | — | — | WO | disclosed |
| WO-2005113551-A1 | BICYCLIC-SUBSTITUTED AMINES HAVING CYCLIC-SUBSTITUTED MONOCYCLIC SUBSTITUENTS | ABBOTT LABORATORIES (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050256309-A1 | Tri-and bi-cyclic heteroaryl histamine-3 receptor ligands | ABBOTT LABORATORIES | 2005-11-17 | — | — | US | disclosed |
| US-20050256118-A1 | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents | ABBOTT LABORATORIES | 2005-11-17 | — | — | US | disclosed |
| US-4386935-A | Process for producing discharge reserve prints on textile materials with amino-azo-benzene dyes | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272736-A1 | Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands | HRH3, HRH4, HRH2 | TDP1 4509/4885CDH1 4193/4885APC 3505/4885 |
| US-20050272728-A1 | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents | HRH3, HRH4, HRH2 | TDP1 4628/4885CDH1 3816/4885APC 2526/4885 |
| US-20050256118-A1 | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents | HRH3, HRH4, HRH2 | TDP1 4628/4885CDH1 3816/4885APC 2526/4885 |
| US-20050256309-A1 | Tri-and bi-cyclic heteroaryl histamine-3 receptor ligands | HRH3, HRH4, HRH2 | TDP1 4509/4885CDH1 4193/4885APC 3505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.