Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 17/20 | 0.53 |
| ▸ | MTOR | P42345 | 14/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | FECH | P22830 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | MELK | Q14680 | 1/20 | 0.52 |
| ▸ | MYLK3 | Q32MK0 | 1/20 | 0.52 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.52 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.52 |
| ▸ | TP53RK | Q96S44 | 1/20 | 0.52 |
| ▸ | ATR | Q13535 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747742 | 0.89 | ATM (0.54) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL15747781 | 0.81 | ATM (0.59) | ATMMTORPIK3CAPIK3CDPIK3CB | |
| SCHEMBL14872807 | 0.81 | MTOR (0.69) | ATMMTORPIK3CAPIK3CDPIK3CB | |
| SCHEMBL3516155 | 0.77 | ATM (0.53) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL2069625 | 0.76 | ATM (0.54) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL15747811 | 0.75 | ATM (0.52) | ATMMTORPIK3CAPIK3CDPIK3CB | |
| SCHEMBL927498 | 0.73 | MTOR (0.68) | ATMMTORPIK3CAPIK3CDPIK3CB | |
| SCHEMBL9905208 | 0.73 | MTOR (0.58) | ATMMTORPIK3CAPIK3CDPIK3CB | |
| SCHEMBL2068197 | 0.73 | ATM (0.46) | ATMMTORPIK3CAPIK3CDPIK3CB | |
| SCHEMBL930048 | 0.73 | MTOR (0.62) | ATMMTORPIK3CAPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |