Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2253693 | 0.94 | RAB9A (0.46) | CYP19A1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL30056169 | 0.94 | RAB9A (0.46) | CYP19A1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL23331882 | 0.89 | RAB9A (0.50) | CYP19A1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL19933574 | 0.85 | NPC1 (0.52) | RAB9ASMN1; SMN2KDM4ENPC1NFKB1 | |
| SCHEMBL20357269 | 0.83 | CYP11B1 (0.48) | CYP19A1RAB9ALMNANPC1MAPK1 | |
| SCHEMBL1416706 | 0.83 | NPC1 (0.55) | RAB9ASMN1; SMN2KDM4ENPC1NFKB1 | |
| SCHEMBL15747736 | 0.82 | NPC1 (0.53) | RAB9ASMN1; SMN2KDM4ENPC1NFKB1 | |
| SCHEMBL15747849 | 0.81 | CYP2A6 (0.59) | CYP19A1LMNASMN1; SMN2KDM4ECYP11B1 | |
| SCHEMBL29472457 | 0.81 | MAPT (0.52) | CYP19A1RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL18090903 | 0.81 | MAPT (0.52) | CYP19A1RAB9ALMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |