SCHEMBL15748909

SCHEMBL15748909

C=CC(=C)CC(=O)Nc1nnc(CCSCCc2nnc(NC(=O)C/C(C)=C/C)s2)s1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLS O94925 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20034327 0.80 GLS (0.49) GLS
SCHEMBL19920118 0.79 GLS (0.57) GLS
SCHEMBL19920381 0.79 GLS (0.59) GLS
SCHEMBL20034437 0.76 GLS (0.49) GLS
SCHEMBL14987610 0.74 GLS (1.00) GLS
SCHEMBL14987158 0.74 GLS (1.00) GLS
SCHEMBL19920384 0.73 GLS (0.53) GLS
SCHEMBL21443360 0.73 GLS (0.54) GLS
SCHEMBL20034420 0.73 GLS (0.55) GLS
SCHEMBL14987008 0.73 GLS (1.00) GLS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014081925-A1 GLUTAMASE INHIBITORS AND METHOD OF USE AGIOS PHARMACEUTICALS, INC. (US) 2014-05-30 WO disclosed