Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740626 | 0.86 | ALDH1A1 (0.36) | IDH1IDH2 | |
| SCHEMBL15740596 | 0.86 | ALDH1A1 (0.36) | IDH1IDH2 | |
| SCHEMBL15740820 | 0.86 | ALDH1A1 (0.36) | IDH1IDH2 | |
| SCHEMBL17447755 | 0.77 | IDH1 (0.38) | IDH1IDH2 | |
| SCHEMBL15749031 | 0.76 | — | — | |
| SCHEMBL15740528 | 0.76 | IDH1 (0.37) | IDH1IDH2 | |
| SCHEMBL15749038 | 0.76 | IDH1 (0.37) | IDH1IDH2 | |
| SCHEMBL15749099 | 0.76 | IDH1 (0.37) | IDH1IDH2 | |
| SCHEMBL15740748 | 0.73 | IDH1 (0.37) | IDH1IDH2 | |
| SCHEMBL19015419 | 0.72 | IDH1 (0.35) | IDH1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014081718-A1 | AMINOPYRIMIDINE COMPOUNDS AS INHIBITORS OF T790M CONTAINING EGFR MUTANTS | GENENTECH, INC. (US) | 2014-05-30 | — | — | WO | disclosed |