Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18551941 | 0.93 | DPP4 (0.48) | DPP4DPP8DPP9CTSCGRM8 | |
| SCHEMBL19005183 | 0.93 | DPP4 (0.48) | DPP4DPP8DPP9CTSCGRM8 | |
| SCHEMBL17793245 | 0.93 | DPP4 (0.48) | DPP4DPP8DPP9CTSCGRM8 | |
| SCHEMBL16421595 | 0.86 | DPP4 (0.54) | DPP4DPP8DPP9CTSCGRM8 | |
| SCHEMBL17985753 | 0.86 | DPP4 (0.54) | DPP4DPP8DPP9CTSCGRM8 | |
| SCHEMBL18073553 | 0.82 | ENPEP (0.36) | DPP4DPP8DPP9CTSCBMP1 | |
| SCHEMBL16330123 | 0.82 | ENPEP (0.36) | DPP4DPP8DPP9CTSCBMP1 | |
| SCHEMBL10267601 | 0.82 | DPP4 (0.54) | DPP4DPP8DPP9GRM8GRM6 | |
| SCHEMBL17986616 | 0.81 | DPP4 (0.42) | DPP4DPP8DPP9CTSCGRM8 | |
| SCHEMBL18519837 | 0.80 | DPP4 (0.45) | DPP4DPP8DPP9CTSCGRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140154702-A1 | Methods For Treating Cancer Using Combination Therapies | ENDOCYTE INC (US) | 2014-06-05 | — | — | US | disclosed |