Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | FOLH1 | Q04609 | 11/20 | 0.67 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.53 |
| ▸ | GNPAT | O15228 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | CPA2 | P48052 | 1/20 | 0.45 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14008770 | 0.96 | ALDH1A1 (0.63) | ALDH1A1FOLH1NAALAD2GNPATMEN1 | |
| SCHEMBL2248714 | 0.89 | GNPAT (0.60) | ALDH1A1FOLH1NAALAD2GNPATRIMKLA | |
| SCHEMBL13467302 | 0.89 | GNPAT (0.60) | ALDH1A1FOLH1NAALAD2GNPATRIMKLA | |
| SCHEMBL19106177 | 0.89 | GNPAT (0.60) | ALDH1A1FOLH1NAALAD2GNPATRIMKLA | |
| SCHEMBL17950968 | 0.89 | GNPAT (0.60) | ALDH1A1FOLH1NAALAD2GNPATRIMKLA | |
| SCHEMBL5551897 | 0.87 | ALDH1A1 (0.85) | ALDH1A1FOLH1GNPATMEN1LMNA | |
| SCHEMBL17948650 | 0.87 | ALDH1A1 (0.85) | ALDH1A1FOLH1GNPATMEN1LMNA | |
| SCHEMBL5551895 | 0.87 | ALDH1A1 (0.85) | ALDH1A1FOLH1GNPATMEN1LMNA | |
| SCHEMBL38657668 | 0.86 | FOLH1 (0.65) | ALDH1A1FOLH1NAALAD2MEN1LMNA | |
| SCHEMBL29400510 | 0.85 | FOLH1 (0.63) | FOLH1NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140154702-A1 | Methods For Treating Cancer Using Combination Therapies | ENDOCYTE INC (US) | 2014-06-05 | — | — | US | disclosed |