Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA4 | P22748 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CTH | P32929 | 1/20 | 0.30 |
| ▸ | CBS | P35520 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270173 | 0.89 | MEN1 (0.39) | MEN1KMT2ACA2NCF1CA12 | |
| SCHEMBL24591513 | 0.89 | MEN1 (0.39) | MEN1KMT2ACA2NCF1CA12 | |
| SCHEMBL12029017 | 0.89 | MEN1 (0.44) | MEN1KMT2ACA2NCF1CA12 | |
| SCHEMBL25241161 | 0.86 | TSHR (0.43) | MEN1KMT2ACA2NCF1CA12 | |
| SCHEMBL24040342 | 0.85 | CA2 (0.34) | MEN1KMT2ACA2NCF1CA12 | |
| SCHEMBL24040332 | 0.85 | MEN1 (0.41) | MEN1KMT2ACA2NCF1CA12 | |
| SCHEMBL5912367 | 0.84 | MEN1 (0.38) | MEN1KMT2ACA2NCF1CA12 | |
| SCHEMBL20017289 | 0.82 | MEN1 (0.41) | MEN1KMT2ACA2NCF1CA12 | |
| SCHEMBL12730446 | 0.81 | TSHR (0.42) | MEN1KMT2ACA2TSHR | |
| SCHEMBL12589997 | 0.81 | TSHR (0.42) | MEN1KMT2ACA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014083505-A1 | METHODS FOR MAKING CONJUGATES FROM DISULFIDE-CONTAINING PROTEINS | NOVARTIS AG (CH) | 2014-06-05 | — | — | WO | disclosed |