Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.50 |
| ▸ | CNR1 | P21554 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17881327 | 0.91 | CNR2 (0.50) | CNR2CNR1ALDH1A1DNM1TSHR | |
| SCHEMBL10397170 | 0.91 | CNR2 (0.50) | CNR2CNR1ALDH1A1DNM1TSHR | |
| SCHEMBL27932908 | 0.89 | CNR2 (0.44) | CNR2CNR1ALDH1A1DNM1TSHR | |
| SCHEMBL2853365 | 0.89 | CNR2 (0.53) | CNR2CNR1ALDH1A1DNM1TSHR | |
| SCHEMBL709665 | 0.88 | CNR2 (0.60) | CNR2CNR1ALDH1A1DNM1TSHR | |
| SCHEMBL17817321 | 0.87 | CNR2 (0.51) | CNR2CNR1ALDH1A1DNM1MAPT | |
| SCHEMBL14980633 | 0.87 | CNR2 (0.51) | CNR2CNR1ALDH1A1DNM1MAPT | |
| SCHEMBL7191931 | 0.87 | CNR2 (0.51) | CNR2CNR1ALDH1A1DNM1MAPT | |
| SCHEMBL19526349 | 0.87 | CNR2 (0.51) | CNR2CNR1ALDH1A1DNM1MAPT | |
| SCHEMBL31087995 | 0.87 | CNR2 (0.51) | CNR2CNR1ALDH1A1DNM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9303051-B2 | Phosphonate ester derivatives and methods of synthesis thereof | CHIMERIX INC. (US) | 2016-04-05 | — | — | US | disclosed |
| US-20150329575-A1 | PHOSPHONATE ESTER DERIVATIVES AND METHODS OF SYNTHESIS THEREOF | EMERGENT BIODEFENSE OPERATIONS LANSING LLC | 2015-11-19 | — | — | US | disclosed |
| US-8569321-B2 | Phosphonate ester derivatives and methods of synthesis thereof | CHIMERIX, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20120058976-A1 | Phosphonate Ester Derivatives and Methods of Synthesis Thereof | CHIMERIX, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-4105629-A | SYNTHETIC RESIN STABILIZER COMPRISING A THIOETHER ESTER AND HINDERED PHENOLIC CARBONATE | ARGUS CHEMICAL CORPORATION (US) | 1978-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058976-A1 | Phosphonate Ester Derivatives and Methods of Synthesis Thereof | PHOSPHO1, PIK3CA, PNP | CNR2 4086/4885CNR1 4055/4885ALDH1A1 2151/4885 |
| US-20150329575-A1 | PHOSPHONATE ESTER DERIVATIVES AND METHODS OF SYNTHESIS THEREOF | PHOSPHO1, PIK3CA, PNP | CNR2 4086/4885CNR1 4055/4885ALDH1A1 2151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.