Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.53 |
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18571160 | 0.91 | DNM1 (0.48) | CNR2CNR1ALDH1A1DNM1TSHR | |
| SCHEMBL31087995 | 0.89 | CNR2 (0.51) | CNR2CNR1ALDH1A1DNM1LMNA | |
| SCHEMBL14980633 | 0.89 | CNR2 (0.51) | CNR2CNR1ALDH1A1DNM1LMNA | |
| SCHEMBL7191931 | 0.89 | CNR2 (0.51) | CNR2CNR1ALDH1A1DNM1LMNA | |
| SCHEMBL27998295 | 0.89 | CNR2 (0.51) | CNR2CNR1ALDH1A1DNM1LMNA | |
| SCHEMBL19526349 | 0.89 | CNR2 (0.51) | CNR2CNR1ALDH1A1DNM1LMNA | |
| SCHEMBL17817321 | 0.89 | CNR2 (0.51) | CNR2CNR1ALDH1A1DNM1LMNA | |
| SCHEMBL17881327 | 0.89 | CNR2 (0.50) | CNR2CNR1ALDH1A1DNM1TSHR | |
| SCHEMBL10397170 | 0.89 | CNR2 (0.50) | CNR2CNR1ALDH1A1DNM1TSHR | |
| SCHEMBL157672 | 0.89 | CNR2 (0.50) | CNR2CNR1ALDH1A1DNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9555166-B2 | Medical device with coating that promotes endothelial cell adherence | ORBUSNEICH MEDICAL INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20150352261-A1 | MEDICAL DEVICE WITH COATING THAT PROMOTES ENDOTHELIAL CELL ADHERENCE | ORBUSNEICH MEDICAL PTE. LTD. (SG) | 2015-12-10 | — | — | US | disclosed |
| US-20150352263-A1 | MEDICAL DEVICE WITH COATING THAT PROMOTES ENDOTHELIAL CELL ADHERENCE | ORBUSNEICH MEDICAL PTE. LTD. (SG) | 2015-12-10 | — | — | US | disclosed |
| US-9072723-B2 | Medical device with coating that promotes endothelial cell adherence | ORBUS MEDICAL TECHNOLOGY INC (US) | 2015-07-07 | — | — | US | disclosed |
| US-20130035755-A1 | MEDICAL DEVICE WITH COATING THAT PROMOTES ENDOTHELIAL CELL ADHERENCE | ORBUSNEICH MEDICAL, INC. (US) | 2013-02-07 | — | — | US | disclosed |
| US-7803183-B2 | Medical device with coating that promotes endothelial cell adherence | ORBUSNEICH MEDICAL, INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-20070156232-A1 | Medical Device with Coating that Promotes Endothelial Cell Adherence | ORBUSNEICH MEDICAL, INC. (US) | 2007-07-05 | — | — | US | disclosed |
| EP-1263484-B1 | COATING WHICH PROMOTES ENDOTHELIAL CELL ADHERENCE | ORBUSNEICH MEDICAL INC (US) | 2007-05-16 | — | — | EP | disclosed |
| US-7037332-B2 | A coating rendering the stent or synthetic graft compatible for in vivo attachment and proliferation of cells on the surface, containing a therapeutical antibody which reacts with an endothelial cell surface antigen | ORBUS MEDICAL TECHNOLOGIES, INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20050043787-A1 | Medical device with coating that promotes endothelial cell adherence | ORBUS MEDICAL TECHNOLOGIES INC. | 2005-02-24 | — | — | US | disclosed |
| EP-1263484-A1 | COATING WHICH PROMOTES ENDOTHELIAL CELL ADHERENCE | Orbus Medical Technologies, Inc. (US) | 2002-12-11 | — | — | EP | disclosed |
| US-20020049495-A1 | Medical device with coating that promotes endothelial cell adherence | ORBUSNEICH MEDICAL PTE. LTD. (SG) | 2002-04-25 | — | — | US | disclosed |
| WO-2001068158-A1 | COATING THAT PROMOTES ENDOTHELIAL CELL ADHERENCE | ORBUS MEDICAL TECHNOLOGIES INC. (US) | 2001-09-20 | — | — | WO | disclosed |
| US-4790951-A | DETERGENTS FOR HARD SURFACES; RESIDUE-FREE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1988-12-13 | — | — | US | disclosed |
| US-4656297-A | HYDROGENATION OF DIMETHYLSUCCINATE IN PRESENCE OF A COPPER CHROMITE CATALYST AND CONTROLLING THE TEMPERATURE | AMOCO CORPORATION (US) | 1987-04-07 | — | — | US | disclosed |
| US-4172961-A | Production of 1,4-butanediol | DENKA CHEMICAL CORPORATION (US) | 1979-10-30 | — | — | US | disclosed |
| US-4032458-A | FROM MALEIC ACID; ESTERIFICATION-DEHYDRATION, HYDROGENATION AND REDUCTION USING COPPER CHROMITE CATALYST | PETRO-TEX CHEMICAL CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |