Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30646 | 0.82 | — | — | |
| SCHEMBL9296112 | 0.76 | — | — | |
| SCHEMBL14941407 | 0.75 | BTN3A1 (0.37) | FDPSBLMTDP1BTN3A1 | |
| SCHEMBL6422693 | 0.75 | BTN3A1 (0.31) | BTN3A1 | |
| SCHEMBL2153742 | 0.74 | — | — | |
| SCHEMBL707277 | 0.72 | — | — | |
| SCHEMBL63983 | 0.71 | FDPS (0.41) | FDPSBLMTDP1BTN3A1 | |
| Propene SCHEMBL15540548 | 0.71 | BTN3A1 (0.37) | FDPSBLMTDP1BTN3A1 | |
| SCHEMBL18128304 | 0.71 | BTN3A1 (0.38) | FDPSBLMTDP1BTN3A1 | |
| SCHEMBL14892928 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483283-B1 | Method for the manufacture of aminohydroxy diphosphonic acids | STRAITMARK HOLDING AG (CH) | 2015-01-07 | — | — | EP | disclosed |
| US-8779135-B2 | Method for the manufacture of aminohydroxy diphosphonic acids | STRAITMARK HOLDING AG (CH) | 2014-07-15 | — | — | US | disclosed |
| US-20120245354-A1 | METHOD FOR THE MANUFACTURE OF AMINOHYDROXY DIPHOSPHONIC ACIDS | STRAITMARK HOLDING AG (CH) | 2012-09-27 | — | — | US | disclosed |
| EP-2483283-A1 | METHOD FOR THE MANUFACTURE OF AMINOHYDROXY DIPHOSPHONIC ACIDS | Straitmark Holding AG (CH) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011039378-A1 | METHOD FOR THE MANUFACTURE OF AMINOHYDROXY DIPHOSPHONIC ACIDS | STRAITMARK HOLDING AG (CH) | 2011-04-07 | — | — | WO | disclosed |
| CN-101106977-A | Direct compression formulation and process | NOVARTIS AG (CH) | 2008-01-16 | — | — | CN | disclosed |