Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31443213 | 0.85 | CYP3A4 (0.60) | TSHRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL7179225 | 0.85 | TSHR (0.78) | TSHRKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27704810 | 0.85 | TSHR (0.46) | TSHRKMT2AMEN1ALDH1A1RAB9A | |
| Benzene SCHEMBL27418497 | 0.84 | ALDH1A1 (0.51) | TSHRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL127127 | 0.84 | NPC1 (0.53) | TSHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL7632492 | 0.84 | KMT2A (0.44) | TSHRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL1569293 | 0.82 | TSHR (0.80) | TSHRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL29535471 | 0.82 | TSHR (0.80) | TSHRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL5510171 | 0.82 | TSHR (0.50) | TSHRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL27664953 | 0.82 | MEN1 (0.47) | TSHRKMT2AMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108102313-B | Dyed polyester master batch and production process thereof | 苏州市苏宏塑料有限公司 | 2020-06-26 | — | — | CN | claimed |
| CN-108102313-B | Dyed polyester master batch and production process thereof | 苏州市苏宏塑料有限公司 | 2020-06-26 | — | — | CN | disclosed |
| US-9441058-B2 | Procatalyst composition with substituted amide ester internal electron donor | W. R. Grace & Co.—Conn. (US) | 2016-09-13 | — | — | US | disclosed |
| US-20140163184-A1 | Procatalyst Composition with Substituted Amide Ester Internal Electron Donor | W. R. GRACE & CO.-CONN. | 2014-06-12 | — | — | US | disclosed |
| CN-101863844-A | Synthesis method of 6, 7-substituent-4-aniline quinazoline | XIANGZHEN BIOLOGY TECHNOLOGY CO LTD | 2010-10-20 | — | — | CN | disclosed |
| CN-87104353-A | The improvement of catalyst productivity in polymerization of olefins | UNION CARBIDE CORP (US) | 1988-03-16 | — | — | CN | disclosed |