SCHEMBL1576844

SCHEMBL1576844

Cc1cccc(C(Cl)=NO)c1Br

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDR P35968 1/20 0.34
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PDE5A O76074 1/20 0.32
PDE1A P54750 1/20 0.32
PDE1B Q01064 1/20 0.32
PDE1C Q14123 1/20 0.32
MGLL Q99685 1/20 0.31
MYC P01106 1/20 0.31
TRPA1 O75762 2/20 0.30
ATM Q13315 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL406588 0.79 TSHR (0.39) HPGDNPC1RAB9A
SCHEMBL406589 0.79 TSHR (0.39) HPGDNPC1RAB9A
SCHEMBL31204265 0.79 TSHR (0.39) HPGDNPC1RAB9A
SCHEMBL2229478 0.76 ALDH1A1 (0.44) KDRALDH1A1KDM4EHPGDHSD17B10
SCHEMBL31315009 0.76 ALDH1A1 (0.44) KDRALDH1A1KDM4EHPGDHSD17B10
SCHEMBL21216758 0.73 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDHSD17B10TRPA1
SCHEMBL16961839 0.73 ALDH1A1 (0.40) KDRALDH1A1KDM4EHPGDHSD17B10
SCHEMBL3928336 0.73 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDHSD17B10TRPA1
SCHEMBL899002 0.71 MEN1 (0.41) ALDH1A1HPGDHSD17B10NPC1RAB9A
SCHEMBL899003 0.71 MEN1 (0.41) ALDH1A1HPGDHSD17B10NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011039276-A1 OXATHIAZINYL(HET)ARYLSULFONYLUREAS, PROCESSES AND INTERMEDIATES FOR PREPARATION THEREOF AND USE THEREOF AS CROP PROTECTION AGENTS AND CROP GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2011-04-07 WO disclosed