SCHEMBL1576965

SCHEMBL1576965

ON=C(Cl)c1cccnc1Br

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.37
TRIM33 Q9UPN9 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
LMNA P02545 1/20 0.36
KDM4E B2RXH2 4/20 0.34
TDP1 Q9NUW8 2/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
BLM P54132 1/20 0.33
AGER Q15109 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NAPRT Q6XQN6 2/20 0.32
HCRTR1 O43613 1/20 0.32
HCRTR2 O43614 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6069388 0.78 SMN1; SMN2 (0.55) SMN1; SMN2LMNAALDH1A1L3MBTL1HPGD
SCHEMBL6069313 0.77 NAPRT (0.53) SMN1; SMN2LMNAKDM4ETDP1ALDH1A1
SCHEMBL29335085 0.77 NAPRT (0.53) SMN1; SMN2LMNAKDM4ETDP1ALDH1A1
SCHEMBL1972194 0.76 SMN1; SMN2 (0.47) TRIM24TRIM33SMN1; SMN2LMNAKDM4E
Hydrochloric Acid SCHEMBL17541418 0.74 SMN1; SMN2 (0.46) TRIM24TRIM33SMN1; SMN2LMNAKDM4E
SCHEMBL899003 0.71 MEN1 (0.41) SMN1; SMN2ALDH1A1HPGDHSD17B10RAB9A
SCHEMBL899002 0.71 MEN1 (0.41) SMN1; SMN2ALDH1A1HPGDHSD17B10RAB9A
SCHEMBL29442955 0.69 KDM4E (0.63) TRIM24TRIM33SMN1; SMN2LMNAKDM4E
SCHEMBL932828 0.69 KDM4E (0.63) TRIM24TRIM33SMN1; SMN2LMNAKDM4E
SCHEMBL12719182 0.68 SMN1; SMN2 (0.36) TRIM24TRIM33SMN1; SMN2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011039276-A1 OXATHIAZINYL(HET)ARYLSULFONYLUREAS, PROCESSES AND INTERMEDIATES FOR PREPARATION THEREOF AND USE THEREOF AS CROP PROTECTION AGENTS AND CROP GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2011-04-07 WO disclosed