SCHEMBL1577095

SCHEMBL1577095

COC(=O)c1cc(Br)ccc1-c1ccc(Br)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 4/20 0.69
KDM4E B2RXH2 2/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2D6 P10635 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
CYP46A1 Q9Y6A2 1/20 0.53
PRKCZ Q05513 1/20 0.50
NR4A2 P43354 1/20 0.49
TP53 P04637 1/20 0.49
MAPT P10636 1/20 0.49
SLC6A4 P31645 3/20 0.49
ALDH1A1 P00352 2/20 0.48
GAA P10253 1/20 0.48
SLC6A2 P23975 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HSD17B10 Q99714 1/20 0.45
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12737920 0.98 SLC6A3 (0.66) SLC6A3KDM4ECYP1A2CYP2D6CYP2C9
SCHEMBL12621155 0.92 CYP46A1 (0.60) SLC6A3KDM4ECYP1A2CYP2D6CYP2C9
SCHEMBL3168568 0.90 SLC6A3 (0.65) SLC6A3KDM4ECYP1A2CYP2D6CYP2C9
SCHEMBL13955082 0.89 SLC6A3 (0.56) SLC6A3KDM4ECYP1A2CYP2D6CYP2C9
SCHEMBL2482051 0.89 NR4A2 (0.54) SLC6A3KDM4ECYP1A2CYP2D6CYP2C9
SCHEMBL12588037 0.89 CYP46A1 (0.68) SLC6A3KDM4ECYP1A2CYP2D6CYP2C9
SCHEMBL1982854 0.87 SLC6A3 (0.61) SLC6A3KDM4ECYP1A2CYP2D6CYP2C9
SCHEMBL19767755 0.86 SLC6A3 (0.69) SLC6A3KDM4ECYP1A2CYP2D6CYP2C9
SCHEMBL1984374 0.85 SLC6A3 (0.58) SLC6A3KDM4ECYP1A2CYP2D6CYP2C9
SCHEMBL21102395 0.85 SLC6A3 (0.62) SLC6A3KDM4ECYP1A2CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023176304-A1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME 住友化学株式会社 2023-09-21 WO disclosed
EP-3093292-B1 METAL COMPLEX AND LIGHT EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL CO (JP) 2021-09-08 EP disclosed
EP-3222625-B1 METAL COMPLEX AND LIGHT-EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL CO (JP) 2019-10-23 EP disclosed
EP-3195378-B1 HOLE TRANSPORTING COMPOSITIONS CAMBRIDGE DISPLAY TECH LTD (GB) 2019-08-21 EP disclosed
EP-3195379-B1 HOLE TRANSPORTING CYCLOBUTENE COMPOUND CAMBRIDGE DISPLAY TECH LTD (GB) 2019-08-21 EP disclosed
US-10270037-B2 Polymers, monomers and methods of forming polymers CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-04-23 US disclosed
US-10270036-B2 Polymer, composition including the polymer, and organic light-emitting device including the polymer SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-04-23 US disclosed
EP-2518111-B1 COMPOSITION AND LUMINESCENT ELEMENT OBTAINED USING SAME SUMITOMO CHEMICAL CO (JP) 2019-03-13 EP disclosed
US-20180226583-A1 CHARGE TRANSFER SALT, ELECTRONIC DEVICE AND METHOD OF FORMING THE SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2018-08-09 US disclosed
US-20180182968-A1 POLYMER COMPOUND, COMPOSITION INCLUDING THE POLYMER COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE POLYMER COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2018-06-28 US disclosed
US-20090043139-A1 Process for the Synthesis of Arylfluorenes and Analogues thereof CDT OXFORD LIMITED (GB) 2009-02-12 US disclosed
US-20090043139-A1 Process for the Synthesis of Arylfluorenes and Analogues thereof CDT OXFORD LIMITED (GB) 2009-02-12 US disclosed
US-7368616-B2 Method for the production of monomers useful in the manufacture of semiconductive polymers MERCK PATENT GMBH (DE) 2008-05-06 US disclosed
US-7368616-B2 Method for the production of monomers useful in the manufacture of semiconductive polymers MERCK PATENT GMBH (DE) 2008-05-06 US disclosed
US-20070210323-A1 Optical Device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2007-09-13 US disclosed
US-20070210323-A1 Optical Device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2007-09-13 US disclosed
EP-1370599-B1 (PARTIALLY) CONJUGATED POLYMER, PROCESS FOR ITS PREPARATION AND USE IN ELECTROLUMINESCENT DEVICES CAMBRIDGE DISPLAY TECH LTD (GB) 2007-08-29 EP disclosed
US-20070093643-A1 Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same SK CORPORATION (KR) 2007-04-26 US disclosed
US-20070034832-A1 (Partially) conjugated polymer, process for its preparation and use in electroluminescent devices CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2007-02-15 US disclosed
US-20070034832-A1 (Partially) conjugated polymer, process for its preparation and use in electroluminescent devices CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2007-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090043139-A1 Process for the Synthesis of Arylfluorenes and Analogues thereof CYP2F1, CYP1A1, AFF1 SLC6A3 4123/4885KDM4E 1059/4885CYP1A2 30/4885
US-10270037-B2 Polymers, monomers and methods of forming polymers PCNA, PARG, PARN SLC6A3 4110/4885KDM4E 3710/4885CYP1A2 1608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.