Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.69 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19956482 | 0.84 | CNR2 (0.78) | CNR2CNR1 | |
| SCHEMBL19956438 | 0.82 | CNR2 (0.78) | CNR2CNR1 | |
| SCHEMBL15788897 | 0.81 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL15774863 | 0.76 | CNR2 (0.72) | CNR2CNR1 | |
| SCHEMBL14226408 | 0.75 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL15774867 | 0.74 | CNR2 (0.69) | CNR2CNR1 | |
| SCHEMBL14151962 | 0.74 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL15774491 | 0.73 | CNR2 (0.72) | CNR2CNR1 | |
| SCHEMBL14242991 | 0.70 | CNR2 (0.57) | CNR2CNR1 | |
| SCHEMBL20057372 | 0.69 | CNR2 (0.63) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928881-A1 | NOVEL PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2015-10-14 | — | — | EP | claimed |
| WO-2014086705-A1 | NOVEL PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-06-12 | — | — | WO | claimed |
| EP-2928881-A1 | NOVEL PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2015-10-14 | — | — | EP | disclosed |
| WO-2014086705-A1 | NOVEL PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-06-12 | — | — | WO | disclosed |