Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.57 |
| ▸ | CNR1 | P21554 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14243475 | 0.84 | CNR2 (0.49) | CNR2 | |
| SCHEMBL14243477 | 0.80 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL20057301 | 0.79 | CNR2 (0.35) | CNR2CNR1 | |
| SCHEMBL14151962 | 0.76 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL14226408 | 0.73 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL14243159 | 0.72 | CNR2 (0.51) | CNR2CNR1 | |
| SCHEMBL20057372 | 0.71 | CNR2 (0.63) | CNR2CNR1 | |
| SCHEMBL15775143 | 0.70 | CNR2 (0.69) | CNR2CNR1 | |
| SCHEMBL20057329 | 0.70 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL19222911 | 0.70 | CNR2 (0.62) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3072886-B1 | PYRIDIN-2-AMIDES USEFUL AS CB2 AGONISTS | HOFFMANN LA ROCHE (CH) | 2018-04-18 | — | — | EP | disclosed |
| EP-3072886-A1 | PYRIDIN-2-AMIDES USEFUL AS CB2 AGONISTS | F. Hoffmann-La Roche AG (CH) | 2016-09-28 | — | — | EP | disclosed |
| WO-2012168350-A1 | PYRIDIN- 2 -AMIDES USEFUL AS CB2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-12-13 | — | — | WO | disclosed |