Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | BCL9 | O00512 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MYOC | Q99972 | 1/20 | 0.50 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27724857 | 0.98 | MGLL (0.56) | MGLLGAAKMT2APKMBCL9 | |
| SCHEMBL27909645 | 0.91 | MGLL (0.53) | MGLLGAAKMT2APKMBCL9 | |
| SCHEMBL28859982 | 0.85 | KMT2A (0.49) | MGLLGAAKMT2APKMBCL9 | |
| SCHEMBL16588595 | 0.85 | MGLL (0.60) | MGLLGAAKMT2APKMBCL9 | |
| SCHEMBL17373926 | 0.85 | MGLL (0.60) | MGLLGAAKMT2APKMBCL9 | |
| SCHEMBL3762920 | 0.84 | MGLL (0.59) | MGLLGAAKMT2APKMBCL9 | |
| SCHEMBL28200212 | 0.83 | GAA (0.53) | MGLLGAAKMT2APKMBCL9 | |
| SCHEMBL11416881 | 0.83 | MGLL (0.55) | MGLLGAAKMT2APKMBCL9 | |
| SCHEMBL2147924 | 0.83 | MGLL (0.58) | MGLLGAAKMT2APKMBCL9 | |
| SCHEMBL13137639 | 0.82 | MGLL (0.57) | MGLLGAAKMT2APKMBCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103491982-B | The polynucleotides delivering in vivo conjugate connected with enzyme sensitiveness | 箭头研究公司 | 2017-09-12 | — | — | CN | disclosed |
| WO-2014086478-A1 | INHIBITORS OF MALT1 PROTEASE | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-12 | — | — | WO | disclosed |
| WO-2014086478-A1 | INHIBITORS OF MALT1 PROTEASE | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-12 | — | — | WO | disclosed |
| CN-102224139-A | Novel 4- (azacycloalkyl) benzene-1, 3-diol compounds as tyrosinase inhibitors, process for their preparation and their use in human medicine and cosmetics | GALDERMA RES & DEV | 2011-10-19 | — | — | CN | disclosed |