Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 12/20 | 1.00 |
| ▸ | TNKS | O95271 | 7/20 | 0.66 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.66 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15791062 | 0.86 | PARP1 (0.77) | PARP1TNKSTNKS2CTSVCTSL | |
| SCHEMBL15775666 | 0.86 | PARP1 (1.00) | PARP1TNKSTNKS2CTSVCTSL | |
| Bromide SCHEMBL15775831 | 0.85 | PARP1 (0.75) | PARP1TNKSTNKS2CTSVCTSL | |
| SCHEMBL15791061 | 0.85 | PARP1 (1.00) | PARP1TNKSTNKS2 | |
| SCHEMBL15569241 | 0.84 | PARP1 (0.73) | PARP1TNKSTNKS2CTSVCTSL | |
| SCHEMBL15775405 | 0.84 | PARP1 (1.00) | PARP1TNKSTNKS2HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL15775429 | 0.84 | PARP1 (0.97) | PARP1TNKSTNKS2 | |
| Bromide SCHEMBL15775373 | 0.84 | PARP1 (0.73) | PARP1TNKSTNKS2 | |
| SCHEMBL15567668 | 0.82 | PARP1 (0.69) | PARP1TNKSTNKS2CTSVCTSL | |
| SCHEMBL15775979 | 0.81 | PARP1 (0.69) | PARP1TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |