⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29185167 | 0.98 | ABCB11 (0.33) | — | |
| Zinc Chloride SCHEMBL29185173 | 0.94 | ABCB11 (0.31) | — | |
| SCHEMBL29185169 | 0.92 | ABCB11 (0.30) | — | |
| SCHEMBL29185166 | 0.92 | ABCB11 (0.30) | — | |
| SCHEMBL3138889 | 0.79 | NOTUM (0.43) | — | |
| SCHEMBL157423 | 0.77 | TSHR (0.37) | — | |
| SCHEMBL1569468 | 0.77 | CSNK2A1 (0.33) | — | |
| SCHEMBL1569578 | 0.77 | — | — | |
| SCHEMBL10607768 | 0.77 | AHR (0.36) | — | |
| SCHEMBL4858324 | 0.76 | CYP3A4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | claimed |
| CN-115611856-B | Piperidine derivative and pharmaceutical composition, preparation method and application thereof | 宜昌人福药业有限责任公司 | 2024-07-05 | — | — | CN | claimed |
| US-20240174603-A1 | MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | RAPPTA THERAPEUTICS OY (FI) | 2024-05-30 | — | — | US | claimed |
| EP-4363403-A1 | PROCESSES FOR THE PREPARATION OF (S)-2-(4-CHLORO-2-METHOXYPHENYL)-2-((3-METHOXY-5-(METHYLSULFONYL)PHENYL)AMINO)-1 -(1H-INDOL-3-YL)ETHENONE DERIVATIVES | Janssen Pharmaceuticals, Inc. (US) | 2024-05-08 | — | — | EP | claimed |
| US-11970485-B2 | RET kinase inhibitors | ELI LILLY AND COMPANY (US) | 2024-04-30 | — | — | US | claimed |
| EP-4345096-A1 | PIPERIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | Yichang Humanwell Pharmaceutical Co., Ltd. (CN) | 2024-04-03 | — | — | EP | claimed |
| CN-117642389-A | Piperidine derivative and pharmaceutical composition, preparation method and application thereof | 宜昌人福药业有限责任公司 | 2024-03-01 | — | — | CN | claimed |
| CN-117642402-A | Spiropiperidine ring derivative and pharmaceutical composition, preparation method and application thereof | 宜昌人福药业有限责任公司 | 2024-03-01 | — | — | CN | claimed |
| EP-4304585-A2 | METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2024-01-17 | — | — | EP | claimed |
| EP-4288412-A1 | MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | Rappta Therapeutics Oy (FI) | 2023-12-13 | — | — | EP | claimed |
| EP-0320201-B1 | 1,2,4,5-Benzoylenebis (naphto [2,3-d] imidazole) compounds and photosensitive members containing them | SHARP KK (JP) | 1994-02-09 | — | — | EP | claimed |
| CN-1030584-A | Novel thiophene derivant and preparation method thereof | TANABE SEIYAKU CO (JP) | 1989-01-25 | — | — | CN | claimed |
| US-4716168-A | STIMULANTS OF IMMUNE RESPONSE | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1987-12-29 | — | — | US | claimed |
| EP-0097425-B1 | FUNGICIDAL OR PLANT GROWTH REGULATING TRIAZOLYL ETHANOLS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-08 | — | — | EP | claimed |
| EP-0187705-A2 | Imidazo(4,5-f)quinolines useful as immunomodulating agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1986-07-16 | — | — | EP | claimed |
| EP-0095640-B1 | ALKYLENE-BRIDGED GUANIDINO-THIAZOLE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BAYER AG (DE) | 1986-01-29 | — | — | EP | claimed |
| EP-0048548-B1 | PHARMACEUTICAL COMPOSITIONS OF FUNGICIDAL TRIAZOLE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | claimed |
| EP-0055850-B1 | DISAZO COMPOUNDS, METHODS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-01 | — | — | EP | claimed |
| EP-0097425-A2 | Fungicidal or plant growth regulating triazolyl ethanols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-01-04 | — | — | EP | claimed |
| EP-0048548-A1 | Pharmaceutical compositions of fungicidal triazole derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-03-31 | — | — | EP | claimed |