Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.65 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19956438 | 0.80 | CNR2 (0.78) | CNR2CNR1 | |
| SCHEMBL17207904 | 0.79 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL15788866 | 0.76 | CNR2 (0.66) | CNR2 | |
| SCHEMBL15788879 | 0.76 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL18098810 | 0.76 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL15790588 | 0.74 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL15788857 | 0.74 | CNR2 (1.00) | CNR2 | |
| SCHEMBL20057521 | 0.71 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL15788870 | 0.71 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL20057301 | 0.70 | CNR2 (0.35) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357918-A1 | NOVEL PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2018-08-08 | — | — | EP | disclosed |
| EP-2928881-B1 | NOVEL PYRIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2018-03-14 | — | — | EP | disclosed |
| WO-2014086705-A1 | NOVEL PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-06-12 | — | — | WO | disclosed |