Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.35 |
| ▸ | CNR1 | P21554 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14242991 | 0.79 | CNR2 (0.57) | CNR2CNR1 | |
| SCHEMBL14243477 | 0.78 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL18098810 | 0.77 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL14243159 | 0.73 | CNR2 (0.51) | CNR2CNR1 | |
| SCHEMBL20057521 | 0.72 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL14243475 | 0.72 | CNR2 (0.49) | CNR2 | |
| SCHEMBL20057373 | 0.69 | CNR2 (0.39) | CNR2CNR1 | |
| SCHEMBL20057359 | 0.69 | CNR2 (0.39) | CNR2CNR1 | |
| SCHEMBL17771901 | 0.68 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL14243341 | 0.64 | CNR2 (0.49) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3072886-B1 | PYRIDIN-2-AMIDES USEFUL AS CB2 AGONISTS | HOFFMANN LA ROCHE (CH) | 2018-04-18 | — | — | EP | disclosed |