Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15789903 | 0.93 | ACACB (0.33) | LNPEPFFAR1 | |
| SCHEMBL15789770 | 0.89 | HRH3 (0.34) | — | |
| SCHEMBL479579 | 0.88 | CHRM3 (0.34) | LNPEPFFAR1PPARGMRGPRX4 | |
| SCHEMBL15789781 | 0.86 | FFAR1 (0.34) | FFAR1MRGPRX4 | |
| SCHEMBL479914 | 0.85 | RXRA (0.33) | LNPEPFFAR1ALOX5APMRGPRX4 | |
| SCHEMBL479858 | 0.85 | MRGPRX4 (0.36) | LNPEPFFAR1ALOX5APPPARGMRGPRX4 | |
| SCHEMBL15789731 | 0.85 | ACACB (0.34) | FFAR1 | |
| SCHEMBL15789813 | 0.82 | HRH3 (0.34) | — | |
| SCHEMBL15789827 | 0.82 | HRH3 (0.34) | — | |
| SCHEMBL479890 | 0.82 | TLR4 (0.33) | ALOX5APMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411361-B1 | 1,1,1-TRIFLUORO-2-HYDROXYPROPYL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2014-06-18 | — | — | EP | claimed |