Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.95 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.95 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19922 | 0.98 | KEAP1 (1.00) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| Hydrochloric Acid SCHEMBL8934456 | 0.95 | KEAP1 (0.95) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| Hydrochloric Acid SCHEMBL11880824 | 0.95 | KEAP1 (0.95) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL8355842 | 0.93 | KEAP1 (0.91) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL179978 | 0.91 | KEAP1 (0.86) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL4033469 | 0.89 | KEAP1 (0.83) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL5903339 | 0.88 | KEAP1 (0.83) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL3200530 | 0.88 | KEAP1 (0.83) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL5988693 | 0.88 | KEAP1 (0.83) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL1703703 | 0.88 | KEAP1 (0.83) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310425-A1 | NOVEL COPOLYMERS AND LUBRICATING COMPOSITIONS THEREOF | The Lubrizol Corporation (US) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010014655-A1 | NOVEL COPOLYMERS AND LUBRICATING COMPOSITIONS THEREOF | THE LUBRIZOL CORPORATION (US) | 2010-02-04 | — | — | WO | disclosed |