Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14613087 | 0.83 | KEAP1 (0.52) | KEAP1SMN1; SMN2SIGMAR1CYP2D6KDM1A | |
| SCHEMBL9801679 | 0.83 | KEAP1 (0.52) | KEAP1SMN1; SMN2SIGMAR1CYP2D6KDM1A | |
| SCHEMBL19336006 | 0.79 | KEAP1 (0.52) | KEAP1SMN1; SMN2SIGMAR1CYP2D6 | |
| SCHEMBL10674628 | 0.78 | DRD3 (0.47) | DRD3DRD1 | |
| SCHEMBL17277324 | 0.78 | KEAP1 (0.46) | KEAP1SMN1; SMN2SIGMAR1KDM1ADRD3 | |
| SCHEMBL9801730 | 0.77 | KEAP1 (0.48) | KEAP1SMN1; SMN2DRD3 | |
| SCHEMBL4000536 | 0.74 | — | — | |
| SCHEMBL4804017 | 0.73 | KEAP1 (0.44) | KEAP1SMN1; SMN2CYP2D6 | |
| SCHEMBL4805342 | 0.73 | KEAP1 (0.44) | KEAP1SMN1; SMN2CYP2D6 | |
| SCHEMBL22317837 | 0.72 | SMN1; SMN2 (0.40) | KEAP1SMN1; SMN2SIGMAR1KDM1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310425-A1 | NOVEL COPOLYMERS AND LUBRICATING COMPOSITIONS THEREOF | The Lubrizol Corporation (US) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010014655-A1 | NOVEL COPOLYMERS AND LUBRICATING COMPOSITIONS THEREOF | THE LUBRIZOL CORPORATION (US) | 2010-02-04 | — | — | WO | disclosed |