Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.43 |
| ▸ | CA2 | P00918 | 10/20 | 0.43 |
| ▸ | CA9 | Q16790 | 8/20 | 0.43 |
| ▸ | CA12 | O43570 | 7/20 | 0.43 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18202965 | 0.93 | CA1 (0.48) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL15805069 | 0.93 | CA1 (0.48) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL10900794 | 0.82 | CA1 (0.46) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL11207674 | 0.82 | CA1 (0.46) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL11214433 | 0.81 | ALDH1A1 (0.50) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL28741168 | 0.80 | CA1 (0.47) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL26952470 | 0.80 | CA1 (0.47) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL3493177 | 0.79 | ALDH1A1 (0.52) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL10628247 | 0.79 | ALDH1A1 (0.52) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL10887383 | 0.79 | ALDH1A1 (0.52) | CA1CA2CA9CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931708-B1 | CYCLOPROPYLBORONIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF | DIVERCHIM (FR) | 2017-05-10 | — | — | EP | disclosed |
| EP-2931708-A2 | CYCLOPROPYLBORONIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF | Diverchim (FR) | 2015-10-21 | — | — | EP | disclosed |
| WO-2014091167-A2 | CYCLOPROPYLBORONIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF | DIVERCHIM (FR) | 2014-06-19 | — | — | WO | disclosed |