Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 3/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15793967 | 1.00 | PIK3CA (0.35) | PIK3CAPRKAA2LIPEHCRTR2LIPG | |
| SCHEMBL15793956 | 1.00 | PIK3CA (0.35) | PIK3CAPRKAA2LIPEHCRTR2LIPG | |
| SCHEMBL15794261 | 1.00 | PIK3CA (0.35) | PIK3CAPRKAA2LIPEHCRTR2LIPG | |
| SCHEMBL15793513 | 1.00 | PIK3CA (0.35) | PIK3CAPRKAA2LIPEHCRTR2LIPG | |
| SCHEMBL14815276 | 0.95 | LIPE (0.38) | PIK3CAPRKAA2LIPELIPG | |
| SCHEMBL14814788 | 0.95 | LIPE (0.38) | PIK3CAPRKAA2LIPELIPG | |
| SCHEMBL15794124 | 0.90 | KMT2A (0.40) | LIPEHCRTR2HCRTR1 | |
| SCHEMBL15794255 | 0.90 | KMT2A (0.40) | LIPEHCRTR2HCRTR1 | |
| SCHEMBL15793870 | 0.90 | KMT2A (0.40) | LIPEHCRTR2HCRTR1 | |
| SCHEMBL15793990 | 0.90 | KMT2A (0.40) | LIPEHCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931727-A1 | DIAZEPINE DERIVATIVES USEFUL AS CALCIUM CHANNEL BLOCKERS IN THE TREATMENT OF PAIN | Abbvie Inc. (US) | 2015-10-21 | — | — | EP | disclosed |
| WO-2014093337-A1 | DIAZEPINE DERIVATIVES USEFUL AS CALCIUM CHANNEL BLOCKERS IN THE TREATMENT OF PAIN | ABBVIE, INC. (US) | 2014-06-19 | — | — | WO | disclosed |