Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 19/20 | 0.77 |
| ▸ | PPARG | P37231 | 2/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12721680 | 0.90 | FFAR1 (0.69) | FFAR1PPARG | |
| SCHEMBL1583980 | 0.90 | FFAR1 (0.74) | FFAR1PPARG | |
| SCHEMBL1583978 | 0.90 | FFAR1 (0.74) | FFAR1PPARG | |
| SCHEMBL12707985 | 0.90 | FFAR1 (0.74) | FFAR1PPARG | |
| SCHEMBL12708097 | 0.89 | FFAR1 (0.60) | FFAR1PPARGHRH3 | |
| SCHEMBL12721661 | 0.89 | FFAR1 (0.64) | FFAR1PPARGHRH3 | |
| SCHEMBL1584318 | 0.88 | FFAR1 (0.63) | FFAR1PPARG | |
| SCHEMBL15801008 | 0.88 | FFAR1 (0.63) | FFAR1PPARG | |
| SCHEMBL1584320 | 0.88 | FFAR1 (0.63) | FFAR1PPARG | |
| SCHEMBL1584432 | 0.88 | FFAR1 (0.69) | FFAR1PPARGHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486005-B1 | PYRROLIDINE GPR40 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2014-06-18 | — | — | EP | disclosed |