Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 18/20 | 0.63 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | RXRB | P28702 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12708107 | 0.89 | FFAR1 (0.50) | FFAR1PPARGNR4A2RXRARXRB | |
| SCHEMBL12721685 | 0.89 | FFAR1 (0.60) | FFAR1PPARG | |
| SCHEMBL15801002 | 0.88 | FFAR1 (0.77) | FFAR1PPARG | |
| SCHEMBL15801060 | 0.87 | FFAR1 (0.66) | FFAR1PPARG | |
| SCHEMBL1583978 | 0.87 | FFAR1 (0.74) | FFAR1PPARG | |
| SCHEMBL1583980 | 0.87 | FFAR1 (0.74) | FFAR1PPARG | |
| SCHEMBL12707985 | 0.87 | FFAR1 (0.74) | FFAR1PPARG | |
| SCHEMBL12721661 | 0.86 | FFAR1 (0.64) | FFAR1PPARG | |
| SCHEMBL1584318 | 0.85 | FFAR1 (0.63) | FFAR1PPARG | |
| SCHEMBL1584320 | 0.85 | FFAR1 (0.63) | FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486005-B1 | PYRROLIDINE GPR40 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2014-06-18 | — | — | EP | disclosed |