Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3081620 | 1.00 | TSHR (0.73) | TSHRCYP2C9LMNAMAOAPTGS1 | |
| SCHEMBL17171595 | 0.88 | LMNA (0.57) | TSHRCYP2C9LMNAMAOAPTGS1 | |
| SCHEMBL9161169 | 0.87 | TSHR (0.66) | TSHRCYP2C9LMNAMAOAPTGS1 | |
| SCHEMBL17034727 | 0.86 | CYP2C9 (0.55) | TSHRCYP2C9LMNAMAOAPTGS1 | |
| SCHEMBL20457828 | 0.84 | CYP2C9 (0.62) | TSHRCYP2C9LMNAALDH1A1 | |
| SCHEMBL11121696 | 0.82 | LMNA (0.52) | TSHRCYP2C9LMNAMAOAPTGS1 | |
| SCHEMBL30173401 | 0.82 | LMNA (0.52) | TSHRCYP2C9LMNAMAOAPTGS1 | |
| SCHEMBL14587067 | 0.82 | LMNA (0.52) | TSHRCYP2C9LMNAMAOAPTGS1 | |
| SCHEMBL12189181 | 0.81 | LMNA (0.52) | TSHRCYP2C9LMNAMAOAPTGS1 | |
| SCHEMBL3081619 | 0.81 | LMNA (0.50) | TSHRCYP2C9LMNAMAOAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914237-B1 | Phosphonate ester antiviral compounds | UNIV CALIFORNIA (US) | 2014-06-18 | — | — | EP | disclosed |