Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17852151 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP3A4CYP1A2TDP1MAPT | |
| SCHEMBL16545684 | 0.98 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP1A2TDP1MAPT | |
| SCHEMBL17231182 | 0.95 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CYP1A2TDP1MAPT | |
| SCHEMBL23310483 | 0.92 | EDNRB (0.40) | ALDH1A1CYP3A4CYP1A2TDP1MAPT | |
| SCHEMBL21959118 | 0.92 | EDNRB (0.40) | ALDH1A1CYP3A4CYP1A2TDP1MAPT | |
| SCHEMBL24416591 | 0.91 | MAPT (0.37) | ALDH1A1CYP3A4CYP1A2TDP1MAPT | |
| SCHEMBL24416592 | 0.91 | MAPT (0.37) | ALDH1A1CYP3A4CYP1A2TDP1MAPT | |
| SCHEMBL20010636 | 0.91 | MAPT (0.37) | ALDH1A1CYP3A4CYP1A2TDP1MAPT | |
| SCHEMBL24031473 | 0.91 | MAPT (0.41) | ALDH1A1CYP3A4CYP1A2TDP1MAPT | |
| SCHEMBL20621541 | 0.89 | EDNRB (0.40) | ALDH1A1CYP3A4CYP1A2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140167028-A1 | AMINOINDOLO[3,2,1-jk]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2014-06-19 | — | — | US | disclosed |
| US-20140167028-A1 | AMINOINDOLO[3,2,1-jk]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2014-06-19 | — | — | US | disclosed |