Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 16/20 | 0.81 |
| ▸ | CHRNA4 | P43681 | 16/20 | 0.81 |
| ▸ | CHRNA7 | P36544 | 14/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15810073 | 1.00 | CHRNB2 (0.81) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL372931 | 0.89 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL1741511 | 0.86 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL372691 | 0.86 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL373003 | 0.86 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL15882741 | 0.86 | CHRNB2 (0.85) | CHRNB2CHRNA4CHRNA7 | |
| Tc-6987 SCHEMBL1459637 | 0.85 | CHRNB2 (0.85) | CHRNB2CHRNA4CHRNA7 | |
| Tc-6987 SCHEMBL1460452 | 0.85 | CHRNB2 (0.85) | CHRNB2CHRNA4CHRNA7 | |
| Tc-6987 SCHEMBL1742025 | 0.85 | CHRNB2 (0.85) | CHRNB2CHRNA4CHRNA7 | |
| Tc-6987 SCHEMBL1741518 | 0.85 | CHRNB2 (0.85) | CHRNB2CHRNA4CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389378-B1 | PREPARATION AND THERAPEUTIC APPLICATIONS OF (2S,3R)-N-2-((3-PYRIDINYL)METHYL)-1-AZABICYCLO[2.2.2]OCT-3-YL)-3,5-DIFLUOROBENZAMIDE | TARGACEPT INC (US) | 2014-06-25 | — | — | EP | disclosed |