Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | POLD1 | P28340 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 14/20 | 0.38 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.36 |
| ▸ | POLG | P54098 | 2/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24858818 | 0.82 | POLA1 (0.40) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL19590285 | 0.74 | POLB (0.43) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL7642196 | 0.73 | POLA1 (0.40) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL16807807 | 0.72 | POLB (0.56) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL21029796 | 0.72 | POLA1 (0.41) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL20879425 | 0.72 | POLA1 (0.41) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL18879958 | 0.71 | POLA1 (0.40) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL3031874 | 0.71 | POLB (0.68) | POLA1POLBPOLD1P2RY2P2RY6 | |
| SCHEMBL265387 | 0.71 | POLB (0.68) | POLA1POLBPOLD1P2RY2P2RY6 | |
| SCHEMBL77582 | 0.71 | POLB (0.68) | POLA1POLBPOLD1P2RY2P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014093924-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2014-06-19 | — | — | WO | disclosed |