SCHEMBL77582

SCHEMBL77582

Cc1cn([C@H]2CC[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.68
POLA1 P09884 1/20 0.68
POLD1 P28340 1/20 0.68
TK1 P04183 6/20 0.55
BCHE P06276 1/20 0.49
DTYMK P23919 2/20 0.49
P2RY2 P41231 1/20 0.47
P2RY6 Q15077 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30586988 1.00 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL3031874 1.00 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL18855348 1.00 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL265387 1.00 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL154177 0.98 POLB (0.65) POLBPOLA1POLD1TK1BCHE
Triphosphate SCHEMBL27892350 0.95 POLB (0.61) POLBPOLA1POLD1TK1BCHE
SCHEMBL28961478 0.94 POLB (0.61) POLBPOLA1POLD1TK1
SCHEMBL3446958 0.93 POLB (0.60) POLBPOLA1POLD1TK1BCHE
SCHEMBL8859644 0.93 POLB (0.61) POLBPOLA1POLD1TK1BCHE
SCHEMBL28543730 0.91 POLB (0.59) POLBPOLA1POLD1TK1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8525 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122095103-A Mutant DNA polymerase and methods of use thereof 2026-05-26 CN claimed
US-12630865-B2 Products and processes for multiplex nucleic acid identification AGENA BIOSCIENCE, INC. (US) 2026-05-19 US claimed
CN-122060854-A Long fragment PCR amplification reaction liquid and application thereof 杭州艾迪康医学检验中心有限公司 2026-05-19 CN claimed
EP-4724611-A2 METHOD FOR RAPIDLY AND ACCURATELY DETECTING HOP LATENT VIROID RNA Colorado Genomics LLC (US) 2026-04-15 EP claimed
US-12597490-B2 Methods and systems for modeling phasing effects in sequencing using termination chemistry Life Technologies Corporation (US) 2026-04-07 US claimed
EP-4368725-B1 A METHOD FOR THE ISOLATION OF DOUBLE-STRAND BREAKS UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) 2026-03-04 EP claimed
EP-4660319-A1 METHOD FOR SEQUENCING OF A DNA STRAND Robert Bosch GmbH (DE) 2025-12-10 EP claimed
US-20250369027-A1 SUBSTRATE CLEAVAGE FOR NUCLEIC ACID SYNTHESIS TWIST BIOSCIENCE CORP (US) 2025-12-04 US claimed
US-20250354208-A1 METHOD FOR SEQUENCING A DNA-STRAND BOSCH GMBH ROBERT (DE) 2025-11-20 US claimed
WO-2025235939-A1 METHODS FOR BALANCED AMPLIFICATION OF SMALL SAMPLES OF NUCLEIC ACIDS ORCHID BIOSCIENCE, INC. (US) 2025-11-13 WO claimed
EP-0480408-B1 Method for the measurement of reverse transcriptase by immobilized primer ASAHI CHEMICAL IND (JP) 1995-09-13 EP claimed
EP-0392459-B1 Method for the measurement of reverse transcriptase by nonradioactive substance ASAHI CHEMICAL IND (JP) 1995-08-09 EP claimed
US-5439793-A Hybridizing two polynucleotide sequences, ligating ends with deoxyribonucleic acid ligase, forming single-stranded polynucleotide having two non-contiguous segments hybridizable with each other SYNTEX (U.S.A.) INC. (US) 1995-08-08 US claimed
WO-1995008647-A1 METHOD FOR CONSTRUCTION OF NORMALIZED cDNA LIBRARIES THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1995-03-30 WO claimed
WO-1994016101-A2 DNA SEQUENCING BY MASS SPECTROMETRY KOESTER HUBERT (US) 1994-07-21 WO claimed
US-5270183-A Device and method for the automated cycling of solutions between two or more temperatures BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE (US) 1993-12-14 US claimed
EP-0480408-A1 Method for the measurement of reverse transcriptase by immobilized primer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1992-04-15 EP claimed
US-5024934-A Incubating a mixture of cell samples, dna polymerase and oligonucleotide primers to facilitate duplication and analyzing THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1991-06-18 US claimed
EP-0392459-A2 Method for the measurement of reverse transcriptase by nonradioactive substance ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1990-10-17 EP claimed
WO-1989008717-A1 DETECTION OF MINIMAL NUMBERS OF NEOPLASTIC CELLS CARRYING DNA TRANSLOCATIONS BY DNA SEQUENCE AMPLIFICATION BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1989-09-21 WO claimed