Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 15/20 | 0.69 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12720709 | 1.00 | GCK (0.69) | GCKFFAR2 | |
| SCHEMBL1581811 | 0.99 | GCK (0.70) | GCKFFAR2 | |
| SCHEMBL13757060 | 0.99 | GCK (0.70) | GCKFFAR2 | |
| SCHEMBL13757089 | 0.89 | GCK (0.72) | GCK | |
| SCHEMBL1581916 | 0.89 | GCK (0.72) | GCK | |
| SCHEMBL12720676 | 0.88 | GCK (0.70) | GCKFFAR2 | |
| SCHEMBL1582188 | 0.88 | GCK (0.70) | GCKFFAR2 | |
| SCHEMBL1581876 | 0.82 | GCK (0.98) | GCK | |
| SCHEMBL13757055 | 0.82 | GCK (0.98) | GCK | |
| SCHEMBL1581823 | 0.82 | GCK (0.68) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585739-B1 | SUBSTITUTED ARYLCYCLOPROPYLACETAMIDES AS GLUCOKINASE ACTIVATORS | LILLY CO ELI (US) | 2011-04-20 | — | — | EP | disclosed |