SCHEMBL1582379

SCHEMBL1582379

N[C@@H](Cc1ccccc1)C(=O)N(CP(=O)(O)O)C(=O)[C@@H](N)Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LAP3 P28838 5/20 0.56
▸ ANPEP P15144 4/20 0.56
▸ ALPI P09923 1/20 0.54
▸ PKM P14618 1/20 0.54
▸ PTGS1 P23219 1/20 0.54
▸ XIAP P98170 1/20 0.54
▸ SLC7A5 Q01650 1/20 0.54
▸ SLC15A1 P46059 1/20 0.47
▸ ACP3 P15309 1/20 0.46
▸ PTPRC P08575 1/20 0.46
▸ LTA4H P09960 1/20 0.45
▸ ERAP1 Q9NZ08 2/20 0.45
▸ ERAP2 Q6P179 1/20 0.45
▸ PTPN1 P18031 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1582673 0.93 ANPEP (0.49) LAP3ANPEPALPIPKMPTGS1
Dl-Phenylalanine SCHEMBL4958176 0.76 SLC7A5 (0.85) LAP3ANPEPALPIPKMPTGS1
Phenylalanine SCHEMBL4958178 0.76 SLC7A5 (0.85) LAP3ANPEPALPIPKMPTGS1
SCHEMBL1582659 0.76 LAP3 (0.49) LAP3ANPEPALPIPKMPTGS1
SCHEMBL12850145 0.76 LAP3 (0.61) LAP3ANPEPALPIPKMPTGS1
SCHEMBL8005620 0.75 ALPI (0.54) ANPEPALPIPKMPTGS1XIAP
SCHEMBL14691646 0.75 ALPI (0.54) ANPEPALPIPKMPTGS1XIAP
SCHEMBL1764633 0.75 ALPI (0.63) ANPEPALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL7645387 0.75 SLC7A5 (0.81) LAP3ANPEPALPIPKMPTGS1
Phenylalanine Amide SCHEMBL15467554 0.75 ALPI (0.63) LAP3ANPEPALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1325024-B1 SELECTIVE GROWTH MEDIA NEWCASTLE UPON TYNE HOSPITALS NAT HEALTH SERVICE TRUST (GB) 2011-04-20 — — EP disclosed
EP-1325024-A1 SELECTIVE GROWTH MEDIA The Newcastle upon Tyne Hospitals National Health Service Trust (GB) 2003-07-09 — — EP disclosed
WO-2002024725-A1 SELECTIVE GROWTH MEDIA NEWCASTLE UPON TYNE HOSPITALS NHS TRUST (GB) 2002-03-28 — — WO disclosed
US-4134972-A OLIGOPEPTIDES HOFFMANN-LA ROCHE INC. (US) 1979-01-16 — — US disclosed
US-4127649-A PEPTIDES HOFFMANN-LA ROCHE INC. (US) 1978-11-28 — — US disclosed
US-4100275-A PEPTIDES HOFFMANN-LA ROCHE INC. (US) 1978-07-11 — — US disclosed
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