Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 2/20 | 0.97 |
| ▸ | RAD1 | O60671 | 1/20 | 0.97 |
| ▸ | RAD51 | Q06609 | 6/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | USP2 | O75604 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | LTA | P01374 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | SENP2 | Q9HC62 | 5/20 | 0.52 |
| ▸ | SENP1 | Q9P0U3 | 5/20 | 0.52 |
| ▸ | SENP3 | Q9H4L4 | 4/20 | 0.52 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.52 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27168234 | 1.00 | P2RY6 (0.97) | P2RY6RAD1RAD51HSD17B10KDM4E | |
| SCHEMBL439381 | 1.00 | P2RY6 (0.97) | P2RY6RAD1RAD51HSD17B10KDM4E | |
| SCHEMBL38213 | 0.98 | P2RY6 (1.00) | P2RY6RAD1RAD51HSD17B10KDM4E | |
| SCHEMBL38212 | 0.98 | P2RY6 (1.00) | P2RY6RAD1RAD51HSD17B10KDM4E | |
| SCHEMBL29350628 | 0.98 | P2RY6 (1.00) | P2RY6RAD1RAD51HSD17B10KDM4E | |
| SCHEMBL29351286 | 0.98 | P2RY6 (1.00) | P2RY6RAD1RAD51HSD17B10KDM4E | |
| SCHEMBL439383 | 0.97 | P2RY6 (0.97) | P2RY6RAD1RAD51HSD17B10KDM4E | |
| SCHEMBL2286120 | 0.97 | P2RY6 (0.97) | P2RY6RAD1RAD51HSD17B10KDM4E | |
| SCHEMBL31481692 | 0.97 | P2RY6 (0.97) | P2RY6RAD1RAD51HSD17B10KDM4E | |
| SCHEMBL11231850 | 0.91 | RAD1 (0.86) | P2RY6RAD1RAD51HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2934110-B1 | USE OF CONNEXIN CHANNEL INHIBITORS TO PROTECT GRAFTS | UNIV GENT (BE) | 2018-08-01 | — | — | EP | claimed |
| US-9485983-B2 | Use of connexin channel inhibitors to protect grafts | UNIVERSITEIT GENT (BE) | 2016-11-08 | — | — | US | claimed |
| US-20150313208-A1 | USE OF CONNEXIN CHANNEL INHIBITORS TO PROTECT GRAFTS | UNIVERSITEIT GENT (BE) | 2015-11-05 | — | — | US | claimed |
| EP-2934110-A1 | USE OF CONNEXIN CHANNEL INHIBITORS TO PROTECT GRAFTS | Universiteit Gent (BE) | 2015-10-28 | — | — | EP | claimed |
| WO-2014095468-A1 | USE OF CONNEXIN CHANNEL INHIBITORS TO PROTECT GRAFTS | UNIVERSITEIT GENT (BE) | 2014-06-26 | — | — | WO | claimed |
| US-20240233860-A1 | METHOD FOR MODELING CYCLIC 3D EPITOPES TO BE USED IN THE DEVELOPMENT OF VACCINES | SYNTHETIC VACCINES LTD (GB) | 2024-07-11 | — | — | US | disclosed |
| EP-3735262-A1 | GLUCOSE OXIDASE COMPOSITIONS AS A NEONATE ANTICONVULSANT | Penn State Research Foundation (US) | 2020-11-11 | — | — | EP | disclosed |
| WO-2019136168-A1 | GLUCOSE OXIDASE COMPOSITIONS AS A NEONATE ANTICONVULSANT | PENN STATE RESEARCH FOUNDATION (US) | 2019-07-11 | — | — | WO | disclosed |
| EP-2934110-B1 | USE OF CONNEXIN CHANNEL INHIBITORS TO PROTECT GRAFTS | UNIV GENT (BE) | 2018-08-01 | — | — | EP | disclosed |
| US-9485983-B2 | Use of connexin channel inhibitors to protect grafts | UNIVERSITEIT GENT (BE) | 2016-11-08 | — | — | US | disclosed |
| US-20150313208-A1 | USE OF CONNEXIN CHANNEL INHIBITORS TO PROTECT GRAFTS | UNIVERSITEIT GENT (BE) | 2015-11-05 | — | — | US | disclosed |
| EP-2934110-A1 | USE OF CONNEXIN CHANNEL INHIBITORS TO PROTECT GRAFTS | Universiteit Gent (BE) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014095468-A1 | USE OF CONNEXIN CHANNEL INHIBITORS TO PROTECT GRAFTS | UNIVERSITEIT GENT (BE) | 2014-06-26 | — | — | WO | disclosed |