SCHEMBL38213

SCHEMBL38213

O=S(=O)(O)c1cc(N=C=S)ccc1C=Cc1ccc(N=C=S)cc1S(=O)(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 2/20 1.00
RAD1 O60671 1/20 1.00
RAD51 Q06609 6/20 0.72
KDM4E B2RXH2 2/20 0.72
USP2 O75604 2/20 0.72
ALDH1A1 P00352 2/20 0.72
LTA P01374 2/20 0.72
CYP3A4 P08684 2/20 0.72
MAPT P10636 2/20 0.72
HPGD P15428 2/20 0.72
P2RX3 P56373 2/20 0.72
HSD17B10 Q99714 2/20 0.72
TDP1 Q9NUW8 2/20 0.72
SENP2 Q9HC62 5/20 0.53
SENP1 Q9P0U3 5/20 0.53
SENP3 Q9H4L4 4/20 0.53
SUMO2 P61956 3/20 0.53
SUMO1 P63165 3/20 0.53
SENP7 Q9BQF6 3/20 0.53
ENPP2 Q13822 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350628 1.00 P2RY6 (1.00) P2RY6RAD1RAD51KDM4EUSP2
SCHEMBL38212 1.00 P2RY6 (1.00) P2RY6RAD1RAD51KDM4EUSP2
SCHEMBL29351286 1.00 P2RY6 (1.00) P2RY6RAD1RAD51KDM4EUSP2
SCHEMBL27168234 0.98 P2RY6 (0.97) P2RY6RAD1RAD51KDM4EUSP2
SCHEMBL2286120 0.98 P2RY6 (0.97) P2RY6RAD1RAD51KDM4EUSP2
SCHEMBL439381 0.98 P2RY6 (0.97) P2RY6RAD1RAD51KDM4EUSP2
SCHEMBL31481692 0.98 P2RY6 (0.97) P2RY6RAD1RAD51KDM4EUSP2
SCHEMBL15823889 0.98 P2RY6 (0.97) P2RY6RAD1RAD51KDM4EUSP2
SCHEMBL439383 0.98 P2RY6 (0.97) P2RY6RAD1RAD51KDM4EUSP2
SCHEMBL11231850 0.93 RAD1 (0.86) P2RY6RAD1RAD51KDM4EUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4318 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059144-A1 DYNAMIC NANOMECHANICAL AMPLIFICATION ANTENNA AND USES SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2025-03-20 WO claimed
US-11725227-B2 Devices and methods for examining drug effects on microorganisms ESSENLIX CORPORATION (US) 2023-08-15 US claimed
US-11725222-B2 Cleavable nucleotide analogs and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-08-15 US claimed
WO-2023069727-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE, INFLAMMATORY, AND IMMUNOLOGICAL DISEASES, AND INFECTIONS EDISON ONCOLOGY (US) 2023-04-27 WO claimed
EP-4121564-A1 BIOMARKERS FOR SACITUZUMAB GOVITECAN THERAPY Immunomedics, Inc. (US) 2023-01-25 EP claimed
US-20220237930-A1 CELL AGE CLASSIFICATION AND DRUG SCREENING FOUNTAIN THERAPEUTICS INC (US) 2022-07-28 US claimed
EP-3244899-B1 PROSTAGLANDIN TRANSPORTER INHIBITORS FOR INHIBITING OVULATION TEL HASHOMER MEDICAL RES INFRASTRUCTURE & SERVICES LTD (IL) 2021-11-24 EP claimed
US-20210338579-A1 pH RESPONSIVE BLOCK COPOLYMER COMPOSITIONS AND MICELLES THAT INHIBIT MCT 1 AND RELATED PROTEINS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-11-04 US claimed
WO-2021188896-A1 BIOMARKERS FOR SACITUZUMAB GOVITECAN THERAPY IMMUNOMEDICS, INC. (US) 2021-09-23 WO claimed
US-20210275693-A1 MODIFIED WOUND DRESSINGS CONVATEC TECHNOLOGIES INC. 2021-09-09 US claimed
US-5705530-A SIDE EFFECT REDUCTION; GLAUCOMA TREATMENT ALLERGAN (US) 1998-01-06 US claimed
EP-0786994-A2 USE OF CHLORIDE CHANNEL BLOCKERS FOR REDUCING INTRAOCULAR PRESSURE Allergan (US) 1997-08-06 EP claimed
US-5565322-A PHOTOELECTRIC DEVICES; DETECTORS; MEDICAL DIAGNOSIS NANOGEN, INC. (US) 1996-10-15 US claimed
US-5559151-A Method for reducing intraocular pressure in the mammalian eye by administration of chloride channel blockers ALLERGAN (US) 1996-09-24 US claimed
US-5532129-A Self-organizing molecular photonic structures based on chromophore- and fluorophore-containing polynucleotides and methods of their use ENTERPRISE PARTNERS II, L.P. (US) 1996-07-02 US claimed
WO-1996016647-A2 USE OF CHLORIDE CHANNEL BLOCKERS FOR REDUCING INTRAOCULAR PRESSURE ALLERGAN (US) 1996-06-06 WO claimed
US-5494932-A AIDS, RETROVIRUSES, HERPES VIRUSES, CYTOMEGALOVIRUS MERRELL DOW PHARMACEUTICALS INC. (US) 1996-02-27 US claimed
EP-0498095-B1 Sulfonic stilbene derivatives in the treatment of viral diseases MERRELL DOW PHARMA (US) 1995-01-04 EP claimed
US-5280015-A 2-substituted adenosines and 2-substituted adenosine 5'-carboxamides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-01-18 US claimed
EP-0498095-A1 Sulfonic stilbene derivatives in the treatment of viral diseases MERRELL DOW PHARMACEUTICALS INC. (US) 1992-08-12 EP claimed